FIMECS Presents at the 6th Targeted Protein Degradation Summit
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Kanagawa, Japan, 26 October 2023 – FIMECS, Inc. (“FIMECS”), a private biotechnology company creating a new class of drugs based on targeted protein degradation, today announced that Toshitake Kobayashi, Ph.D., Vice President of FIMECS, will make a presentation at the 6th Targeted Protein Degradation Summit (30th October-2nd November 2023 in Boston, MA, USA). Title is “Exploring Suitable E3 Ligases for Targeted Protein Degradation by Phenotypic-First Strategy”. In this presentation, improvement of the RaPPIDSTM platform for expanding the landscape of E3 ligases by phenotypic-first approach that make degrader discovery more efficient will be introduced.
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About FIMECS, Inc.
FIMECS, Inc. is developing a new class of drugs based on targeted protein degradation for the currently ‘undruggable’ targets in immuno-oncology and oncology areas. The company became able to discover drug candidates for inducing the degradation of disease-relevant targeted proteins by integrating proprietary E3 ligase binders and RaPPIDSTM platform. This drug discovery platform will help providing drugs to the patients all over the world through various internal and collaboration projects. https://www.fimecs.com/eng/
RaPPIDSTM (Rapid Protein Proteolysis Inducer Discovery System) is one of the proprietary drug discovery platforms of FIMECS, Inc. used to generate therapeutic candidates of the targeted protein degrader. The platform allows synthesizing and evaluating various degraders quickly based on the company’s proprietary know-how and diversity-oriented synthesis, and delivery of the drug candidates with the best combination of target protein binders, linkers, and E3 ligase binders. Moreover, RaPPIDSTM platform enables the discovery of novel E3 ligase binders, which is expected to dramatically expand the range of target proteins that can be degraded.
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