Publications

2020

The auxin-inducible degron 2 technology provides sharp degradation control in yeast, mammalian cells, and mice

Aisha Yesbolatova, Yuichiro Saito, Naomi Kitamoto, Hatsune Makino-Itou, Rieko Ajima, Risako Nakano, Hirofumi Nakaoka, Kosuke Fukui, Kanae Gamo, Yusuke Tominari, Haruki Takeuchi, Yumiko Saga, Ken-ichiro Hayashi and Masato T. Kanemaki, Nat Commun. 11, 5701 (2020).

DOI: 10.1038/s41467-020-19532-z

 

An Efficient Approach Toward Drugging Undruggable Targets

Kanae Gamo, Naomi Kitamoto, Masato T. Kanemaki, and Yusuke Tominari (2020), Hilmar Weinmann and Craig Crews (eds.), Protein Degradation with New Chemical Modalities: Successful Strategies in Drug Discovery and Chemical Biology, London, The Royal Society of Chemistry, p167-183.

DOI: 10.1039/9781839160691

 

標的タンパク質分解誘導技術と創薬ベンチャーの動向

Yusuke Tominari and Kanae Gamo, Exp. Med. 38(14), 2020, p2342-2347.

Link: https://www.yodosha.co.jp/jikkenigaku/book/9784758125352/index.html

 

蛋白質分解誘導剤の開発

Mitsutoshi Wayama, Kanae Gamo, and Yusuke Tominari, J. Mol. Targeted Ther. Cancer, 18(1), 2020, p56-62.

Link: https://www.m-review.co.jp/magazine/detail/J0081_1801

 

ファイメクス社の標的タンパク分解誘導技術

Yusuke Tominari, Farumasia, 56(3), 2020, p248-250.

DOI: 10.14894/faruawpsj.56.3_248

 


2019

Ligand-induced genetic degradation as a tool for target validation

Aisha Yesbolatova, Yusuke Tominari, and Masato T. Kanemaki. Drug Diecovery Today, Volume 31, April 2019, p91-98.

DOI: 10.1016/j.ddtec.2018.11.001